18 Top Berberine Supplements for SIBO Relief

Discover the best berberine supplement for SIBO to boost your gut health, with quick insights and top choices for effective, natural support.
BrandMy RatingPrice
Toniiq
Great Budget Performer
8.6/10
Thorne
Best for Gut Health
8.8/10
Integrative Therapeutics
Best for Metabolic Support
8.8/10
Integrative Therapeutics
Best for Bacterial Balance
9.0/10
Nutriflair
8.6/10

Best Berberine Supplement for Sibo

Struggling with SIBO can feel like navigating a maze of discomfort and uncertainty, but finding the right supplement can be a game-changer. Among the contenders, berberine shines brightly as a potent ally, offering hope and healing in a compact, powerful package. Let’s explore the best berberine supplements to help you regain control and restore balance with confidence and clarity.

Great Budget Performer: Toniiq

Toniiq Ultra High Strength Berberine HCl 500mg from The Himalayas - Berberine Supplement - 97% Tested Purity Extract - Wild Harvested - Concentrated Berberine 500mg Supplements -90 Veggie Capsules
Highlights
High Purity (97%)
Wild-Harvested Himalayan
Third-Party Tested

The Toniiq Berberine stands out as a great budget performer thanks to its exceptional 97% purity and wild-harvested Himalayan roots.

This means you're getting a powerful, bioavailable extract without breaking the bank.

Although each capsule contains only 450mg and requires multiple doses, the high-quality sourcing, rigorous third-party testing, and GMP-certified manufacturing ensure you're boosting your health with trust and transparency.

For anyone seeking reliable berberine support that’s affordable and potent, Toniiq is a smart choice.

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Price history for Toniiq on Amazon

Best for Gut Health: Thorne

THORNE Berberine 1000 mg per Serving - Botanical Supplement - Support Heart Health, Immune System, Healthy GI, Cholesterol - Gluten-Free, Dairy-Free - 60 Capsules - 30 Servings
Highlights
Supports healthy microbiome
Third-party certified
Trusted by professionals

Thorne Berberine 1000 mg truly earns its title as the "Best for Gut Health".

It supports a healthy microbiome and beneficial gut bacteria, which is essential for SIBO management.

Plus, its third-party testing guarantees purity and potency, giving you confidence in every dose.

Trusted by professionals and athletes alike, Thorne combines efficacy with quality.

Keep in mind, some users experience minor bowel changes or discomfort, so starting with a lower dose might be wise.

Overall, if gut health is your priority, this supplement is a solid choice to consider.

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Price history for Thorne on Amazon

Best for Metabolic Support: Integrative Therapeutics Berberine

Integrative Therapeutics Berberine - 1000–1500 mg Daily - Berberine HCL Supplement for Metabolic Support* - Gluten-Free & Vegan Supplements for Men & Women - 60 Capsules
Highlights
Supports metabolic health
High-quality & tested
Vegan & gluten-free

Our team selected this berberine supplement as Best for Metabolic Support because it delivers a potent 1000-1500 mg daily dose, specifically targeting carbohydrate and lipid metabolism.

Backed by solid science and trusted by physicians, this supplement is designed to support your cellular energy in a clean, vegan, and gluten-free capsule.

While some users might experience mild stomach discomfort or find the capsules a bit large, the high quality and rigorous US testing make it a reliable choice.

If metabolic health is your goal, this one definitely deserves a spot on your shortlist.

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Price history for Integrative Therapeutics Berberine on Amazon

Best for Bacterial Balance: Integrative Therapeutics Berberine

Integrative Therapeutics - Berberine Complex - Berberine Supplement with Oregon Grape and Goldenseal Root Extract - Vegan Supplement - 90 Capsules
Highlights
Supports healthy bacteria
Trusted by physicians
Gluten-free and vegan

Integrative Therapeutics' Berberine Complex is a solid choice for supporting bacterial balance.

Its blend includes Oregon Grape and Goldenseal Root Extract, known traditional agents for helping maintain healthy gut microbiota.

Plus, it’s trusted by physicians and backed by science, giving you peace of mind.

It's gluten-free, vegan, and free of artificial additives, making it suitable for many dietary needs.

While it may offer limited gastro improvements and calls for dosage adjustments in some cases, its focus on bacterial harmony makes it an excellent addition to your gut health routine.

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Price history for Integrative Therapeutics Berberine on Amazon

NutriFlair

NutriFlair Premium Berberine HCL 1200mg, 120 Capsules - Plus Pure True Ceylon Cinnamon, Berberine HCI Root Supplements Pills - Immune System, Healthy Weight Management
Highlights
Supports glucose management
Vegan and non-GMO
Third-party tested

NutriFlair’s Berberine with Ceylon Cinnamon offers a powerful 1200 mg dose of berberine combined with 100 mg of pure Ceylon cinnamon, making it a robust choice for managing SIBO symptoms.

The formula supports glucose metabolism and helps promote a healthy gut, while being vegan, non-GMO, and free from common allergens.

We appreciate its third-party testing and strict manufacturing standards, ensuring quality and safety.

While some users might experience minor stomach discomfort, many find it a trusted, effective supplement that fits into a health-conscious lifestyle.

Overall, NutriFlair stands out as a reliable option with a satisfaction guarantee.

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Price history for NutriFlair on Amazon

Nutreb Berberine

Berberine Supplement 1200mg - 5X Higher Absorption - Ultra Pure 98% Berberine HCL - Healthy Weight Management, Immune Support - Non GMO, Manufactured in USA - 60 Vegan Capsules
Highlights
High absorption rate
Pure & vegan
Made in USA

Nutreb's Berberine supplement is a game-changer for SIBO management.

Its unique 1200mg potency combined with 98% purity ensures you're getting maximum bang for your buck.

The 5X higher absorption thanks to BioPerine means faster results, helping to curb those pesky symptoms quicker.

Plus, it’s made in the USA with vegan, non-GMO capsules free from artificial fillers—perfect for a health-conscious approach.

While we note some users might experience minor side effects, overall, it offers a potent boost to your metabolic health and gut wellness.

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Price history for Nutreb Berberine on Amazon

Double Wood Berberine Berberine Supplement for Sibo

Berberine Supplement 500mg, 60 Capsules (Third Party Tested, Non-GMO, Gluten Free, Vegan Safe) AMPK Activator - Berberine HCL for Cardiovascular Health by Double Wood
Highlights
Supports cardiovascular health
Effective appetite suppression
High-quality, third-party tested

Double Wood's Berberine capsules offer a powerful blend of cardiovascular support and AMPK activation, which can aid in healthy aging and metabolic regulation.

The single-dose capsules make it simple to stay consistent, and the 2-month supply ensures you get the most value.

Plus, it's crafted in the USA with strict testing for microbes and heavy metals, providing peace of mind.

While some users might experience mild stomach discomfort, the high-quality ingredients and rigorous testing standards make this a trustworthy choice for SIBO support and overall wellness.

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Price history for Double Wood Berberine on Amazon

Pure Encapsulations Berberine

Pure Encapsulations Berberine UltraSorb | Enhanced Absorption Berberine | 60 Capsules
Highlights
Enhanced bioavailability (550 mg)
Supports metabolic health
Trusted, premium ingredients

The 550 mg of bioavailable berberine phytosome ensure you get more bang for your buck, making it a solid choice for supporting metabolic and cardiometabolic health.

It’s crafted with pure, premium ingredients that are tested for potency and purity, which is great for those with sensitivities.

While it’s on the pricier side and results can sometimes vary for blood sugar control, the trusted formulation and high-quality sourcing make it worth considering in your health toolkit.

Overall, a reliable option for targeted support.

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Price history for Pure Encapsulations Berberine on Amazon

Doctor Recommended Supplements

DOCTOR RECOMMENDED SUPPLEMENTS Berberine Plus 1200mg Per Serving - 120 Veggie Capsules with Royal Jelly
Highlights
High potency 1200mg
Pure, single ingredient
Trusted quality standards

The Max Potency! 1200 Mg Pure Berberine delivers a powerful dose that effectively supports a healthy system, especially for those battling SIBO.

Made from a single, high-quality ingredient—Berberine HCl—it's about purity and effectiveness.

The capsules are all-natural, free of artificial additives, and produced right here in the USA under strict third-party testing standards.

While some may find the capsules' taste a bit strong or need to watch for sensitivities, we appreciate the trusted brand behind it and their satisfaction guarantee.

Overall, a reliable, potent choice for your wellness arsenal.

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Price history for Doctor Recommended Supplements on Amazon

Carlyle Berberine with Ceylon Cinnamon Berberine Supplement for Sibo

Carlyle Berberine with Ceylon Cinnamon | 2000mg Complex | 60 Capsules | Vegetarian, Non-GMO, Gluten Free
Highlights
Effective appetite control
High-quality ingredients
Easy to swallow

Carlyle’s Berberine and Ceylon Cinnamon Complex delivers a potent 2,000 mg per vegetarian capsule, making it a powerhouse for supporting SIBO management.

The blend of natural ingredients is rooted in wellness, and the quality is top-notch — laboratory tested with clean, non-GMO, allergen-free ingredients.

While results in the short term may vary and some cravings might linger initially, many users appreciate its effectiveness in appetite control and the ease of swallowing.

It’s a smart choice for those seeking a high-quality, well-rounded supplement on their health journey.

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Price history for Carlyle Berberine with Ceylon Cinnamon on Amazon

ForestLeaf Berberine

Berberine Supplement 1300mg per Serving- 97% Tested Ultra High Potency Berberine HCl with Ceylon Cinnamon, Bitter Melon & Gymnema, 10:1 Extract Berberis Supplements, Weight Management, 90 Veggie Caps
Highlights
High Purity & Potency
Supports Energy Levels
Includes Botanical Support

ForestLeaf's Full Spectrum Berberine offers an ultra-pure 97% extract, giving you a potent dose in just two capsules.

The addition of botanical allies like Ceylon cinnamon and bitter melon enhances its support for your gut and energy metabolism—a real bonus for SIBO fighters.

While some users report mixed results, the quality is undeniable, with third-party testing and USA-made standards.

It's a bit pricier, but if you're after maximum purity and a holistic plant-based boost, this berberine is a solid choice on your health journey.

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Price history for ForestLeaf Berberine on Amazon

Nature's Bounty

Nature's Bounty 1000mg Berberine Herbal Health Capsules Support Heart and Cardiovascular Health, Help Maintain Healthy Cholesterol, Triglyceride, and Blood Sugar Levels, 60 Capsules
Highlights
Supports cardiovascular health
Plant-based alkaloid source
Convenient capsule dosage

Nature’s Bounty Berberine 1000mg offers a potent, plant-based supplement that supports your cardiovascular health effortlessly.

Just two capsules a day supply a full month’s worth of organic berberine from the bark of natural plants—easy and convenient!

Plus, it’s non-GMO, gluten-free, and vegetarian-friendly, aligning with modern clean-label standards.

Built on 50 years of expertise, this brand emphasizes quality and scientific backing.

That said, as with any supplement, some users report minor stomach or bowel discomfort, and occasional breaks may be beneficial.

Overall, it’s a reliable, trusted choice for SIBO and heart health support.

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Price history for Nature's Bounty on Amazon

Thorne Berberine Berberine Supplement for Sibo

THORNE Berberine - 200 mg (Formerly Berbercap) - Supports Heart Function, Immune System and Gut Health - 60 Capsules
Highlights
Supports immune health
Made from Indian Barberry
High-quality, pure ingredients

Made from Indian Barberry, this supplement offers a broad-spectrum approach to supporting a healthy immune system, which is crucial for managing SIBO.

It also promotes healthy mucus membranes in your respiratory tract and helps maintain normal gut flora, essential for balancing digestive health.

Thorne is known for its commitment to pure, high-quality ingredients—free from gluten, soy, dairy, and other common allergens—which gives us confidence in its safety.

While some users might experience digestive upset, its clean formulation and moderate dosing make it a solid choice for those seeking a natural support boost.

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Price history for Thorne Berberine on Amazon

NOW Berberine Glucose Support

NOW Supplements, Berberine Glucose Support, Combined with MCT Oil for Optimal Berberine Absorption, 90 Softgels
Highlights
Supports glucose metabolism
Enhanced absorption with MCT
Natural plant ingredients

The inclusion of capric acid (a nifty medium-chain triglyceride) really helps boost absorption, making sure you get the most out of every capsule.

The natural plant ingredients, like goldenseal and Oregon grape, are supported by clinical data showing their positive effects on glucose and lipid metabolism—key for SIBO sufferers.

While the large capsule size might be a challenge for some, the overall formula promotes gastrointestinal comfort and effective absorption.

With a solid 4.4-star rating from satisfied users, it’s clear this supplement is worth considering for your health routine.

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Price history for NOW Berberine Glucose Support on Amazon

CaelumCore Berberine

Liposomal Berberine HCL - Berberine 1500mg Activates AMPK & GLP-1, High Bioavailability Berberines Supplement for Women and Men, Berberine Plus Overall Health Support (1 Pack)
Highlights
High bioavailability technology
Potent 1500mg dose
Supports energy & appetite

CaelumCore's Liposomal Berberine HCL delivers a powerful, 1500 mg dose in just two capsules, thanks to cutting-edge liposomal tech that boosts absorption by 6X.

This means you get more bioavailable support for your gut and metabolism without packing extra pills.

The supplement also activates GLP-1, helping you feel fuller longer and supporting healthier eating habits.

Made in the USA with premium, GMO-free ingredients, it’s a reliable choice for those seeking energy, better nutrient utilization, and overall gut health.

A smart pick for SIBO warriors!

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Price history for CaelumCore Berberine on Amazon

Luma Nutrition Berberine Berberine Supplement for Sibo

Luma Nutrition Berberine Supplement - Berberine HCL 1200mg Per Serving - Vegan, Gluten Free, Non-GMO - 60 Capsules
Highlights
High potency 1200mg dose
Pure, high-quality extract
Enhanced bioavailability technology

The potent 1200mg dose packed into each capsule means you're getting serious support for blood sugar regulation and energy levels.

Made from high-quality Berberina from the barberry plant, it guarantees purity and potency, with enhanced bioavailability technology that helps your body absorb more efficiently.

We do note that some users might experience mild nausea initially, and it's recommended to take cycles to avoid tolerance.

Overall, with its clean ingredients and trusted manufacturing, this supplement stands out as a top-tier choice for SIBO management and metabolic health.

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Price history for Luma Nutrition Berberine on Amazon

Decent Nature Berberine

Organic Berberine with Ceylon Cinnamon 2175mg - Premium berberine supplement high purity extract USDA Organic, support immune system, Berberine Plus Complex, Non-GMO Vegan for Men Women 90 Capsules
Highlights
Supports immunity
Activates AMPK enzyme
Organic, non-GMO formula

Nature’s Superior Formula packs a punch with 2,175 mg of Organic Berberine and Ceylon Cinnamon in every capsule, supporting your immune system and helping to activate your body’s AMPK enzyme—crucial for managing carbs and mitigating SIBO symptoms.

The organic, non-GMO ingredients ensure you're fueling your body with clean, natural power.

While it requires consistent use to see results, it’s a reliable choice for boosting overall wellness and stability.

Overall, it’s a balanced blend for those looking to optimize gut health while supporting energy and immunity.

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Price history for Decent Nature Berberine on Amazon

NutraHarmony

Berberine with Ceylon Cinnamon | Apple Cider Vinegar | Hawthorn Berry | Citrus Bergamot | Bitter Melon - 14-in-1 Supplement for Heart Support, Metabolism & Energy - Made in USA - Vegan, 60 Capsules
Highlights
Supports Heart & Metabolism
Made in USA Quality
Holistic Nutritional Blend

The Berberine Blend Capsules deliver a comprehensive approach to health, combining heart and metabolism support with a carefully curated mix of ingredients like Turmeric, Ginseng, and Beet Root.

The advanced complex ensures you're getting not just Berberine, but a holistic boost to your vitality.

Made in the USA and rigorously quality-checked, it offers peace of mind with every capsule.

While it’s not SIBO-specific, its potent formula and reliable sourcing make it a top choice for those prioritizing overall well-being.

A solid, trustworthy supplement for consistent results.

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Price history for NutraHarmony on Amazon

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