17 Top Creams for Leg Cramps at Night

Discover the best cream for leg cramps at night to soothe those restless muscles quickly and comfortably. Find your perfect relief in just a few moments.
BrandMy RatingPrice
Theraworx
Best for Quick Relief
9.0/10
Magnilife
Best for Relaxing Legs
8.4/10
Hyland's
Best Low-Cost Alternative
8.8/10
Magnilife
Best for Relaxing Legs
8.4/10
Magnilife
8.4/10

Best Cream for Leg Cramps at Night

Struggling to find restful nights amid stubborn leg cramps can feel like an uphill battle through a swamp of discomfort. Luckily, the right cream can become your soothing ally, melting away cramps with velvety ease. Dive into our curated guide to discover the best options to keep your legs happy and restore peaceful sleep.

Best for Quick Relief: Theraworx

Theraworx Relief for Muscle Cramps Foam Fast-Acting Muscle Spasm, Leg Soreness with Magnesium Sulfate - 7.1 oz - 1 Count
Highlights
Quick relief from cramps
Absorbs fast, no mess
Effective for multiple muscles

As the best for quick relief, this foam works fast to soothe those pesky leg cramps and muscle spasms that often strike at night.

Its rapid absorption means relief is just moments away, helping you get back to restful sleep without any mess or fuss.

We also appreciate that it's effective across multiple muscle groups, making it versatile for different discomforts.

However, the noticeable scent could be a turnoff for sensitive noses.

Overall, if you're seeking immediate and mess-free relief, this foam is a solid choice that delivers on its promises.

Be sure to also check out the best cream for leg cramps for more options! Also, here is the price history so you know exactly when to buy!

Price history for Theraworx on Amazon

Best for Relaxing Legs: MagniLife

MagniLife Relaxing Leg Cream PM, Deep Penetrating Topical for Pain and Restless Leg Syndrome Relief, Naturally Soothe Cramping, Discomfort, and Tossing with Lavender and Magnesium - 4oz
Highlights
Natural pain relief
Fast-acting ingredients
No side effects

As "Best for Relaxing Legs," this deep-penetrating cream truly delivers on its promise.

Infused with calming lavender and magnesium, it helps soothe those tense, restless legs that keep you tossing at night.

The natural herbal blend feels luxurious and non-greasy, making application before bedtime an easy routine.

While results can vary from person to person, many find relief quickly without any harsh side effects or dependency concerns.

It’s a safe, plant-based option that genuinely helps you wind down and enjoy a more restful sleep.

Be sure to also check out the best cream for leg circulation for more options! Also, here is the price history so you know exactly when to buy!

Price history for MagniLife on Amazon

Best Low-Cost Alternative: Hyland's

Hyland's Leg Cramps Ointment, Arnica Gel Leg Cramp Relief, Natural Relief of Calf, Leg and Foot Cramp, 2.5 oz
Highlights
Quick relief
Natural ingredients
Easy to apply

Hyland's Leg Cramps Ointment offers natural and quick relief with its soothing arnica-infused formula.

It warms as you apply, instantly calming those pesky leg cramps during the night. Perfect for sensitive skin, since it's free from harsh chemicals like aspirin or ibuprofen.

Although the relief is shorter-lasting and may require frequent reapplications, its ease of use and natural ingredients make it a top contender for anyone seeking a gentle, budget-friendly option.

For a trustworthy natural remedy, this ointment is definitely worth considering.

Be sure to also check out the best cream for acanthosis nigricans for more options! Also, here is the price history so you know exactly when to buy!

Price history for Hyland's on Amazon

MagniLife

MagniLife Relaxing Leg Cream, Deep Penetrating Topical for Pain and Restless Leg Syndrome Relief, Naturally Soothe Cramping, Discomfort, and Tossing with Lavender and Magnesium - 4oz
Highlights
Natural, plant-based ingredients
Fast-acting relief
Non-greasy formula

MagniLife’s penetrating leg cream offers a natural, plant-based solution for restless nights caused by leg cramps.

The herbal blend, including magnesium, aloe, lavender, and sage, works quickly to soothe and relax your legs without the greasy residue.

It’s safe, non-greasy, and drug-free—perfect for those seeking a gentle alternative to medications.

While results can vary and reapplication might be needed, we love how it provides a fast, calming relief that helps you fall asleep peacefully.

Say goodbye to tossing and turning and hello to refreshed mornings!

Be sure to also check out the best bra for copd patients for more options! Also, here is the price history so you know exactly when to buy!

Price history for MagniLife on Amazon

MagniLife

MagniLife Pain Relieving Foot Cream Soothing Relief for Soreness, Pain, Burning, Tingling, Itching or Sensitivity in Feet & Legs - All-Natural Moisturizing Topical - Petroleum-Free - 4oz Tube
Highlights
Natural pain relief
Non-greasy formula
Safe for sensitive skin

Our team loves that it offers natural pain relief with ingredients like beeswax, eucalyptus, and camphor, providing soothing comfort without harsh chemicals.

The non-greasy formula absorbs well and feels lightweight on the skin, perfect for those nighttime routines.

It's safe for sensitive skin and can be used on various areas, including legs and hands—making it versatile for different needs.

While it doesn't deliver instant relief and requires some patience, the gentle, plant-based ingredients make it a trustworthy choice for persistent leg cramps.

Overall, a solid, soothing option for restful nights.

Be sure to also check out the best tea for lymph drainage for more options! Also, here is the price history so you know exactly when to buy!

Price history for MagniLife on Amazon

Dersie Magnesium Cream Cream for Leg Cramps at Night

Dersie Magnesium Cream for Sleep & Leg Cramps: Soothing Magnesium Lotion with Lavender, Grape & Camellia Seed Oil - Hydrating & Calming for Men, Women and Kids (4 fl oz)
Highlights
Soothes muscle tension
Absorbs quickly
Natural ingredients

Dersie Magnesium Cream is a fantastic choice for easing nighttime leg cramps.

Its rich formula delivers 250 mg of pure magnesium per teaspoon, which helps support muscle relaxation and promotes a sense of calm for restful sleep.

The natural ingredients like magnesium chloride and plant extracts hydrate and soothe your skin while providing quick relief.

Its easy, mess-free application means you can effortlessly integrate it into your nightly routine.

While it may not completely banish severe cramps, the soothing sensation and nourishing feel make it a trusted partner for gentle, consistent relief.

Be sure to also check out the best tea for diverticulitis for more options! Also, here is the price history so you know exactly when to buy!

Price history for Dersie Magnesium Cream on Amazon

Theraworx

Theraworx Relief for Muscle Cramps Roll-On Fast-Acting Muscle Spasm, Leg Soreness with Magnesium Sulfate - 2.5 oz - 2 Count
Highlights
Fast-acting relief
No-mess application
Natural ingredients

The fast-acting formula quickly soothes muscle cramps, helping you get back to sleep without delay.

Its easy no-touch application eliminates mess and odor, making it super convenient to use even in the dark.

Made with natural ingredients, it's safe for daily use without worrying about harsh chemicals.

While it may take a few pumps for some, once absorbed, it offers reliable relief.

Compact and travel-friendly, this cream is a winner for nighttime comfort.

Overall, it’s a practical, soothing option that combines ease with effectiveness.

Be sure to also check out the best period cramp massager for more options! Also, here is the price history so you know exactly when to buy!

Price history for Theraworx on Amazon

Nakery SkinRecovery

Nakery SkinRecovery Ultra Strength Massage Cream - Muscle Relaxer Cream & Magnesium Cream for Leg Cramps with Menthol - Fast Absorbing Feet Cream - Non-Sticky Leg Cramp Cream for Soothing Comfort
Highlights
Fast-absorbing formula
Multi-use for relaxation
Supports better sleep

The ultra-strength magnesium formula works swiftly to ease those night-time leg cramps, making it a game-changer for restless nights.

Its fast-absorbing nature means you don’t have to wait around or deal with sticky residues—just smooth, quick relief.

Plus, its multi-use versatility makes it perfect for targeting tired muscles anywhere—from calves to shoulders—boosting circulation and relaxation.

While it has a limited scent profile and short-lived effects, its soothing botanical blend and supportive design make it a solid choice for anyone seeking better sleep and muscle relief.

Be sure to also check out the best leg cramp cream for more options! Also, here is the price history so you know exactly when to buy!

Price history for Nakery SkinRecovery on Amazon

Pharmapulse Cream for Leg Cramps at Night

Pharmapulse Neuropathy Nerve Relief Cream – Maximum Strength for Feet, Hands, Legs, Toes, Lower Back - Alpha Lipoic Acid, Arnica, Vitamin B6, Aloe Vera, MSM - Effective Soothing
Highlights
Effective relief with consistent use
Nice creamy, non-greasy texture
Pleasant, fresh scent

The Pure Sciences Relief Cream delivers effective relief with consistent use, especially for those nightly leg cramps.

Its nice, creamy texture absorbs quickly without any greasy residue, which makes applying it a breeze.

Plus, the pleasant, fresh scent adds a subtle touch of comfort to your bedtime routine.

While it may not provide immediate relief, the calming ingredients work well over time.

Just a heads-up—reading the instructions can be tricky, and the menthol scent isn’t for everyone.

Still, for many, it’s a reliable addition to nightly self-care.

Be sure to also check out the best pads for sesamoiditis for more options! Also, here is the price history so you know exactly when to buy!

Price history for Pharmapulse on Amazon

Dr. Joel's

Neuropathy Cream - Maximum Strength Nerve Relief Cream for Feet, Hands, Legs- 4 OZ Large - Made in USA
Highlights
Quick, lasting relief
All natural ingredients
Large value pack

Dr.

Joel’s Cream delivers quick, long-lasting relief with its all-natural formula, perfect for tackling those frustrating nighttime leg cramps.

The herbal oils and arnica work synergistically to soothe muscles and nerves, helping you get peaceful sleep.

Plus, the generous 4oz jar offers great value — more product, fewer worries about running out.

While some reviewers note a strong scent and varying effectiveness, we appreciate the organic ingredients and the confidence behind the GMP and ISO certifications.

Overall, a natural, potent choice for nighttime relief.

Be sure to also check out the best tea for autophagy for more options! Also, here is the price history so you know exactly when to buy!

Price history for Dr. Joel's on Amazon

Arvesa Hemp Cream

Hemp Cream Maximum Strength - Soothing Relief for Back, Neck, Feet & Nerves, Hands, Muscle and Joint Support - All-Natural Formula - Hemp Oil Gel Rub with MSM - Glucosamine, Turmeric, Arnica - 4 FL OZ
Highlights
Fast, non-greasy absorption
Effective muscle relief
All-natural ingredients

This advanced hemp cream delivers quick, targeted relief that penetrates deeply without leaving a greasy residue.

The all-natural blend of Arnica, MSM, and Turmeric makes it ideal for soothing nighttime leg cramps, soothing muscles while supporting overall wellness.

While some users might be sensitive to its scent or experience a slight burning sensation, these side effects are often mild and temporary.

Its high-quality US formulation assures safety and efficacy, making it a trustworthy choice for anyone seeking fast relief from nightly cramps.

Overall, this cream packs a punch with its natural ingredients and strong performance.

Be sure to also check out the best brace for peroneal tendonitis for more options! Also, here is the price history so you know exactly when to buy!

Price history for Arvesa Hemp Cream on Amazon

Hyland's Leg Cramps PM Cream for Leg Cramps at Night

Hyland's, Leg Cramps PM Tablets, Nighttime Formula, Natural Relief of Calf, Foot and Leg Cramps at Night, Quick Dissolving Tablets, 50 Count
Highlights
Quick-dissolving, fast relief
Natural homeopathic ingredients
Effective for nighttime cramps

The quick-dissolving tablets melt effortlessly under your tongue, providing fast relief from those pesky nighttime leg cramps.

The natural homeopathic ingredients are gentle yet effective, helping you ease not only cramps in your calves, feet, and legs but also any associated sleeplessness.

Plus, it’s a safe choice without drug interactions, making it suitable for the whole family.

While the chalky taste might take some getting used to and the dosage is limited per bottle, its effectiveness and natural approach earn it a solid spot in our top recommendations for restful, cramp-free sleep.

Be sure to also check out the best bra for hiatal hernia for more options! Also, here is the price history so you know exactly when to buy!

Price history for Hyland's Leg Cramps PM on Amazon

Theraworx

THERAWORX Relief Fast-Acting Foam for Leg & Foot Cramps and Muscle Soreness, 3.4oz Travel Size
Highlights
Fast relief action
Effective for cramps
Safe, gentle ingredients

Cramp Defense is a game-changer when it comes to night-time leg cramps.

Its fast-acting formula quickly soothes muscle spasms, helping you get back to sleep without delay.

Made with safe and gentle ingredients, it’s perfect for those who want effective relief without harsh chemicals.

While the bottle is a bit small, its potent formulation means you don’t need to use much each time—making it last longer than expected.

Overall, if you’re after a reliable, quick fix for cramps, this product hits the mark with a promising 4.4-star rating.

Be sure to also check out the best wrap for heel pain for more options! Also, here is the price history so you know exactly when to buy!

Price history for Theraworx on Amazon

MagniLife

MagniLife Relaxing Leg Cream, Deep Penetrating Topical for Pain and Restless Leg Syndrome Relief, Naturally Soothe Cramping, Discomfort, and Tossing with Lavender and Magnesium - 2 Packs of 4oz
Highlights
Natural ingredients
Fast-acting relief
Safe with medications

MagniLife Penetrating Leg Cream harnesses the power of all-natural ingredients like magnesium, aloe, lavender, and sage, making it a soothing and herbal choice for nighttime cramps.

Its deep, non-greasy formula offers fast-acting relief without any dependency worries, making it a safe, plant-derived option—ideal if you're already on medication or prefer herbal solutions.

While it relies on topical application and results can vary, many users appreciate its gentle, natural approach to calming restless legs.

Overall, a trusted choice for those seeking a more holistic remedy for nighttime cramps.

Be sure to also check out the best crystals for fertility for more options! Also, here is the price history so you know exactly when to buy!

Price history for MagniLife on Amazon

Nuturna Cream for Leg Cramps at Night

Sciatica Nerve Cream - Maximum Strength Comfort Cream for Feet, Hands, Legs, Toes, Back - Natural Ultra Strength Arnica, MSM, Menthol, Soothing Comfort, Large 4 Oz
Highlights
Natural and safe ingredients
Fast-acting soothing relief
Made in the USA

This Max Strength Sciatica Cream is packed with a potent natural blend—think Arnica, Vitamin B6, MSM, Aloe Vera, and Vitamin E—that work together to target discomfort and provide long-lasting relief.

The fast-acting formula delivers a cooling, calming sensation that quickly soothes those night-time leg cramps.

Plus, it's made in the USA with natural ingredients, so you can feel good about applying it regularly.

While it might not handle severe pain for everyone, its lightweight, non-greasy texture makes it easy to use daily, making it a solid choice for gentle relief and comfort.

Be sure to also check out the best wipes for blepharitis for more options! Also, here is the price history so you know exactly when to buy!

Price history for Nuturna on Amazon

Wagomars Magnesium Cream

Magnesium Cream for Sleep - Topical Magnesium Lotion for Leg Cramps & Pain, Muscle Relaxation, Calm - Natural Body Butter for Deep Hydration - Safe for Kids (Lavender)
Highlights
Deep muscle relief
Natural and organic
Calms tension

The Wagomars Magnesium Cream delivers deep muscle relief thanks to its mineral-rich sea salt content, targeting the fatigue that keeps you awake at night.

Its 100% natural ingredients make it a safe choice for even the most sensitive skin.

While it may not specifically eliminate cramps, it does a fantastic job calming tension and relaxing muscles, which can help ease nighttime discomfort.

Plus, the soothing scent and calming properties contribute to a more restful sleep.

Overall, it’s a natural, versatile option perfect for those seeking gentle muscle relaxation before bed.

Be sure to also check out the best books for health anxiety for more options! Also, here is the price history so you know exactly when to buy!

Price history for Wagomars Magnesium Cream on Amazon

Ortho Sleeper Sleeve

Sleeper Sleeves Can Stop and Prevent Night Leg and Foot Cramps - The Original Easy On, Easy Off - Made in USA - Maximum Calf Size - 14 1/2 INCH Circumference - DO NOT Exceed, Pain Will Increase
Highlights
Effective nighttime relief
Easy to put on
Clinically Proven

The Leg Cramp B'Gone Sleeper Sleeve offers effective nighttime relief thanks to its scientifically-backed design.

It’s easy to slip on, providing quick and targeted support without any hassle.

Crafted from soft, breathable materials, it stays comfortable all night long.

However, keep in mind the size restrictions—it’s best for calves up to 14.5 inches—and some users might experience pressure pain if the fit isn't just right.

Overall, it’s a promising solution for those desperate to prevent and ease leg cramps with minimal effort.

Be sure to also check out the best wrap for sprained wrist for more options! Also, here is the price history so you know exactly when to buy!

Price history for Ortho Sleeper Sleeve on Amazon

🎯 Popular Posts

Never Miss A Post!

Sign up for free to Chronic Care Central and be the first to get notified about updates.

Never Miss A Post! 🎉
Subscribe to our newsletter and get the latest deals and news
  • 01Get discounts on products and memberships
  • 02Get notified about new posts, reviews and updates
subsc