19 Muscle Pain Relief Sprays for Fast Comfort

Discover the best muscle pain relief spray to soothe soreness fast. Quick, effective relief for your active lifestyle, all in a few refreshing sprays.
BrandMy RatingPrice
Icy Hot
Great Budget Performer
9.0/10
Biofreeze
Best for Fast Relief
9.2/10
Theraworx
Best for Muscle Cramps
9.0/10
Theraworx
Best for Post-Workout Soreness
8.8/10
Penetrex
8.4/10

Best Muscle Pain Relief Spray

Struggling with stubborn muscle aches that refuse to quit? Discover the ultimate relief with our expertly curated list of the best muscle pain relief sprays—designed to deliver swift, soothing comfort right where you need it most. Whether you’re an athlete or just tired of soreness, these sprays promise a quick escape from discomfort, turning pain into mere distant memories.

Great Budget Performer: Icy Hot

Icy Hot Original Pain Relief Dry Spray with 16% Menthol, Pain Relief for Muscles & Joints, 4 oz.
Highlights
Fast-acting relief
Non-greasy application
Works at any angle

Icy Hot Original Dry Spray is a great budget performer that delivers quick relief when you need it most.

Its fast-acting formula helps ease muscle pain, backaches, and minor injuries with just a few spritzes—no greasy residue involved.

The spray works at any angle, making application super convenient, especially if you're on the go.

While it may be a bit pricier per ounce and comes in a small bottle, its trusted brand status and reliable results make it a smart choice for those seeking effective relief without breaking the bank.

Be sure to also check out the best pain relieving spray for more options! Also, here is the price history so you know exactly when to buy!

Price history for Icy Hot on Amazon

Best for Fast Relief: Biofreeze

Biofreeze 13572 Professional Menthol Pain Relieving Spray 4 FL oz, Arthritis, Simple Backaches and Joint Pain, Pack of 2
Highlights
Fast muscle relief
Less messy application
Quick cold sensation

Biofreeze Professional Menthol Spray earns its spot as Best for Fast Relief.

The rapid cooling sensation kicks in almost immediately, providing that satisfying, icy feel that targets muscle and joint discomfort quickly.

Its easy, less messy application makes it a convenient choice for on-the-go relief, and most users appreciate the quick absorption, so you don’t have to wait around for results.

However, the strong menthol scent and a slightly tricky spray button might take some getting used to.

Overall, if you're after swift, effective muscle relief, this spray deserves a top spot in your toolkit.

Be sure to also check out the best oral sleep spray for more options! Also, here is the price history so you know exactly when to buy!

Price history for Biofreeze on Amazon

Best for Muscle Cramps: Theraworx

Theraworx Relief for Muscle Cramps Roll-On Fast-Acting Muscle Spasm, Leg Soreness with Magnesium Sulfate - 2.5 oz - 1 Count
Highlights
Fast-acting relief
No-mess application
Natural ingredients

It’s specifically formulated to target muscle cramps and spasms, providing fast-acting relief right when you need it.

The no-touch application makes it super convenient—simply press and go, no mess or strong odor to worry about.

Made with natural ingredients, it’s safe for daily use, which is a huge plus for ongoing relief.

While it might not work instantaneously for everyone and is best suited for cramps rather than other muscle issues, its compact size makes it perfect for on-the-go relief.

Overall, a savvy choice for quick, natural muscle cramp soothing.

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Price history for Theraworx on Amazon

Best for Post-Workout Soreness: Theraworx

Theraworx Relief for Muscle Cramps Spray Fast-Acting Muscle Spasm, Leg Soreness with Magnesium Sulfate - 7.1 oz - 1 Count
Highlights
Fast-acting relief
Natural ingredients
No mess, odorless

This spray is a game-changer after tough workouts.

It relieves muscle cramps and spasms quickly, thanks to its fast absorption formula.

Made with natural ingredients, it’s safe for daily use and leaves no mess or strong odor—perfect for on-the-go recovery.

While the dispenser can clog sometimes and offers limited spray angles, these minor quirks don’t overshadow its effectiveness.

Overall, if you're looking for a gentle, natural solution that works fast and keeps things hassle-free, this is a fantastic choice for post-workout soreness.

Be sure to also check out the best magnesium spray for muscle pain for more options! Also, here is the price history so you know exactly when to buy!

Price history for Theraworx on Amazon

Penetrex

Penetrex Penetrex Joint & Muscle Therapy - Soothing Comfort for Back, Neck, Hands, Feet - Premium Whole Body Rub with Arnica, Vitamin B6 MSM & Boswellia - Non-Greasy 2oz Cream
Highlights
Deep, natural ingredient blend
Non-greasy and odored
Trusted by 2M users

Penetrex’s proprietary blend of natural ingredients like arnica, vitamin B6, and MSM truly sets it apart.

It penetrates deeply to target discomfort at the source, providing a soothing experience without the greasy residue or overpowering odor common with other creams.

Trusted by over 2 million users, it’s perfect for tackling joint and muscle pain across your entire body—from knees to neck.

While it’s not a miracle cure, consistent application offers noticeable relief over time, helping you get back to your day with confidence.

A reliable choice for those who value quality ingredients and effective results.

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Price history for Penetrex on Amazon

Aspercreme

Aspercreme Lidocaine Dry Spray Soothes Aggravated Nerves, Numbing Topical Pain Relief Spray with Max-Strength 4% Lidocaine Sprays at Any Angle, 4 Oz.
Highlights
Fast-acting relief
Discreet fragrance-free formula
Non-greasy, quick dry

Aspercreme Lidocaine Pain Relief Dry Spray delivers rapid numbness to nerve pain, making it perfect for quick relief on the go.

Its discreet, fragrance-free formula means no awkward scents or greasy residue—just quick-drying, mess-free application.

Plus, since it works at any angle, you don't have to worry about getting it right side up.

While the 4-ounce size is a bit limited and it mainly targets nerve pain, its maximum-strength lidocaine puts powerful relief right at your fingertips.

For effective, fuss-free relief, Aspercreme stands out as a top choice.

Be sure to also check out the best ice pack for heel pain for more options! Also, here is the price history so you know exactly when to buy!

Price history for Aspercreme on Amazon

Biofreeze Muscle Pain Relief Spray

Biofreeze Menthol Spray 3 FL OZ Colorless Aerosol Spray Associated with Sore Muscles, Arthritis, Simple Backaches, and Joint Pain (Packaging May Vary) (1)
Highlights
Fast-acting cooling sensation
Easy spray application
Trusted by professionals

Biofreeze’s top-tier spray technology delivers a rapid cooling sensation that soothes muscle pain almost instantly.

The 360° continuous flow spray makes application super easy, even when you're reaching awkward spots or applying upside down.

As a clinically recommended brand trusted by healthcare professionals worldwide, it offers peace of mind that you're using a reliable, effective solution.

Plus, it’s made with USP-grade menthol and is cruelty-free, aligning with eco-conscious choices.

The only caveats?

The strong menthol scent and a slightly higher price point, but for fast relief, Biofreeze remains a top contender.

Be sure to also check out the best homeopathic nasal spray for allergies for more options! Also, here is the price history so you know exactly when to buy!

Price history for Biofreeze on Amazon

Icy Hot Max

Icy Hot Max Strength Pain Relief Spray with Lidocaine Plus Menthol, 4 Ounces
Highlights
Fast-acting relief
No-mess spray application
Long-lasting effect

The Icy Hot Max Strength Dry Spray is a game-changer for quick pain relief.

Its rapid action penetrates deep to desensitize nerves and soothe muscle aches at the push of a button.

The no-mess spray dries instantly and works at any angle, making application effortless even during a quick break.

Plus, being from America’s top topical pain reliever brand, it offers reliable, long-lasting relief.

While the strong menthol scent might be a bit intense and it’s best suited for minor pains, the overall effectiveness and ease of use make it a top contender in muscle pain relief.

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Price history for Icy Hot Max on Amazon

TIDL Cryotherapy Pain Relief Spray

TIDL Cryotherapy Pain Relief Spray, 3 Oz, Targeted Neck Pain, Joint & Muscle Pain Relief, Organic, Plant-Based Menthol, Instant Cooling for Arthritis, Back & Knee Pain
Highlights
Fast-acting relief
Easy, non-sticky application
Supports quick recovery

TIDL Pain Relief Spray delivers quick relief with a cooling sensation thanks to its combination of Arnica and Menthol—perfect for post-workout recovery or everyday aches.

Its easy, quick-drying formula means no sticky residue, and the 360-degree spray technology ensures we can cover hard-to-reach spots effortlessly.

While it might run if not rubbed in properly and the relief doesn't last all day, it's ideal for short-term, targeted relief on the go.

Backed by science and designed for active lifestyles, this spray keeps us moving without interruptions.

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Price history for TIDL Cryotherapy Pain Relief Spray on Amazon

AleveX Muscle Pain Relief Spray

AleveX Pain Relieving Spray, Fast Acting & Fast Drying for Targeted Pain Relief, 3.2 oz Spray
Highlights
Powerful ingredients
No mess application
Fast, long-lasting relief

Its powerful ingredients like Camphor and maximum-strength Menthol 16% deliver quick, targeted relief for muscle soreness and joint pain.

The no-drip, mess-free spray makes application a breeze—no more greasy hands or wasted product.

Plus, it works fast and provides long-lasting cooling relief that keeps discomfort at bay.

The scent can be quite strong and lingering, which might be a drawback for some, but if you handle the odor, this spray offers a reliable, effective solution for quick muscle pain relief.

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Price history for AleveX on Amazon

Boiron Arnicare

Boiron Arnicare Gel for Soothing Relief of Joint Pain, Muscle Pain, Muscle Soreness, and Swelling from Bruises or Injury - Non-greasy and Fragrance-Free - 2.6 oz
Highlights
Fast absorption
Natural pain relief
Effective for bruises

This non-greasy, water-based gel absorbs swiftly, providing quick relief after injuries or intense workouts. Made with natural Arnica montana, it offers a soothing, plant-based approach to easing muscle pain and reducing swelling — ideal for those seeking a gentle, homeopathic solution.

While it may not banish pain instantly or work long-term without repeated use, it’s perfect for quick relief and bruise healing.

Plus, the unscented, paraben-free formula makes it suitable for sensitive skin.

Overall, a reliable, natural remedy to have on hand for muscle discomfort.

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Price history for Boiron Arnicare on Amazon

Stopain

Stopain Pain Relief Spray 4oz, USA Made, Max Strength Fast Acting with Menthol, MSM, Glucosamine for Lower Back, Arthritis, Knee, Neck, Joints, HSA FSA Approved OTC Topical Analgesic Product
Highlights
Stops pain quickly
Immediate penetrating relief
Trusted USA brand

Stopain maximum strength pain relief spray delivers what it promises: immediate, penetrating relief that stops aches in their tracks.

Its fast-acting menthol formula works on contact, providing a soothing sensation without the greasy residue or strong odors common in other options.

Made in the USA with trusted ingredients, it’s a reliable choice for those seeking professional-grade recovery without invasive procedures.

Plus, with added MSM and Glucosamine, it helps support joint mobility along the way.

Just keep in mind, a little overspray can go a long way—and delivery delays might happen.

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Price history for Stopain on Amazon

Theraworx Muscle Pain Relief Spray

Theraworx Relief for Muscle Cramps Foam Fast-Acting Muscle Spasm, Leg Soreness with Magnesium Sulfate - 7.1 oz - 1 Count
Highlights
Effective muscle relief
Quick absorption
No mess, no odor

Its effective relief for muscle cramps and spasms is truly standout, offering quick respite when you need it most.

It absorbs rapidly, so you won’t be waiting forever to feel the benefits — perfect for those busy days.

The formula is no mess and no strong odor, making it convenient to use anytime, anywhere.

The only caveat is its somewhat strong scent, which might not suit everyone, and limited scent options.

Overall, it’s a solid choice for fast, mess-free muscle relief when you’re in a pinch.

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Price history for Theraworx on Amazon

Biofreeze

Biofreeze, Colorless, 4 Fl Oz (Pack of 3)
Highlights
Effective muscle pain relief
Easy to use rollerball
Quick cooling sensation

The effective muscle pain relief it provides is noticeable within minutes, thanks to its powerful cooling sensation.

The easy-to-use rollerball design makes application a breeze—perfect for quick relief on the go.

Although it does have a slight menthol smell and a strong cooling effect, these are minor trade-offs for such reliable results.

While it can be a bit pricey, its proven performance keeps it at the top of our list.

If you're seeking rapid, targeted relief with minimal fuss, this spray might just become your new best friend.

Be sure to also check out the best scale for drugs for more options! Also, here is the price history so you know exactly when to buy!

Price history for Biofreeze on Amazon

Tiger Balm Active Muscle Spray

Tiger Balm Active Muscle Spray, 2.53 fl. oz. – Sports Spray Muscle Rub Spray – Analgesic Spray for Muscles – Spray for Back Discomfort, & More – Relieving Spray for Soreness
Highlights
Fast, effective relief
Non-greasy application
Ideal for hard-to-reach areas

Tiger Balm Active Muscle Spray delivers quick and targeted relief with a cooling sensation that feels great on sore muscles.

Its non-greasy formula makes application a breeze—no sticky residue or staining, perfect before or after your workout.

The spray's long-lasting soothing formula with methyl salicylate, menthol, and camphor works effectively on hard-to-reach spots like your back or shoulders.

While its strong scent might not be everyone's favorite, many users find it worth the relief.

Keep in mind, the aerosol requires some precautions, but overall, it’s a reliable choice for active individuals seeking fast relief.

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Price history for Tiger Balm Active Muscle Spray on Amazon

DCH Labs Muscle Pain Relief Spray

5% Lidocaine Numbing Spray Maximum Strength Relief, 5 oz, Topical Anesthetic That Sprays at Any Angle, Vegan & Cruelty-Free, Secured with Child Resistant Cap
Highlights
Maximum strength relief
Deep nerve penetration
Touchless application

Its maximum strength 5% lidocaine quickly delivers deep, fast-acting relief for muscle soreness, nerve pain, and discomfort.

The touchless spray system makes it super convenient to reach those tricky areas, even upside down.

Plus, it's odor-free and infused with soothing aloe vera, vitamin E, cucumber, and chamomile, keeping things non-greasy and comfortable.

While there’s a brief initial burn, it’s a small trade-off for the fast, targeted numbness.

Overall, a reliable choice for swift, mess-free relief — ideal for on-the-go pain management.

Be sure to also check out the best ice pack for neck for more options! Also, here is the price history so you know exactly when to buy!

Price history for DCH Labs on Amazon

Terramed

Fast Acting Leg Cramp Relief Aerosol Spray | Pain Relief for Muscle Spasms, Soreness, & Foot and Calf Cramps | Homeopathic Medicine for Restless Legs Syndrome Relief
Highlights
Fast-acting relief
Natural, non-greasy ingredients
No sticky residue

This pharmacist-recommended spray offers rapid, targeted relief that really hits the spot.

It’s perfect for quickly soothing those stubborn leg cramps, muscle spasms, and stiffness, especially in the foot and calf areas.

What we love most is its fast-absorbing, non-greasy formula — no sticky residue here!

Plus, the natural ingredients make it a clean, mess-free solution, so you can apply it on the go without any hassle.

While it does have a menthol scent and taste, the effectiveness more than makes up for it.

Overall, it’s a reliable, portable option for anyone seeking fast and natural muscle relief.

Be sure to also check out the best ice pack for balls for more options! Also, here is the price history so you know exactly when to buy!

Price history for Terramed  
on Amazon

Blue Emu

Blue Emu Pain Relief Spray for Muscle, Joint & Bruises Fast Drying Support w/Emu Oil, 4oz
Highlights
Fast-acting relief
Odor-free formula
Versatile spray application

The Blue-Emu Pain Relief Spray stands out thanks to its speedy action—the deep-penetrating formula hits hard and fast, so you don’t have to wait long to feel relief.

Its odor-free nature makes it convenient for daily use without any awkward smells, and the 360-degree spray ensures you can target muscles and joints from any angle, perfect for those hard-to-reach spots.

Whether you're dealing with a quick muscle twinge or chronic aches, this spray offers versatile application to keep you moving comfortably—compact and efficient for on-the-go relief.

Be sure to also check out the best massage ball for sciatica for more options! Also, here is the price history so you know exactly when to buy!

Price history for Blue Emu on Amazon

Fast Freeze Muscle Pain Relief Spray

Fast Freeze All-Natural Cooling Pain Relief Therapy: Continuous Spray, 4 fl oz, packaging may vary
Highlights
Quick pain relief
Deep tissue cooling
All-natural ingredients

Fast Freeze's powerful cooling sensation penetrates deep into tired muscles, offering rapid relief from aches, strains, and post-workout stiffness.

The all-natural formula with menthol, aloe, vitamin E, and holly extract means you're treating your body gently—no harsh chemicals here!

Plus, it dries quickly and leaves no greasy or stained residues, making it a mess-free fix after a long day.

While the scent is quite strong and it’s on the pricier side, the effectiveness makes it a top contender for anyone seeking soothing, immediate relief.

Be sure to also check out the best shoe inserts for neuroma for more options! Also, here is the price history so you know exactly when to buy!

Price history for Fast Freeze on Amazon

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