17 Top OTC Hemorrhoid Suppositories for Fast Relief

Discover the best OTC hemorrhoid suppositories to soothe discomfort swiftly. Your quick guide to relief with top-rated options tailored for you.
BrandMy RatingPrice
Rugby Laboratories
Best Cheap Pick
8.0/10
Boiron
Best for Postpartum Recovery
8.6/10
Ariella
Best for Natural Relief
9.2/10
Preparation H
Best for Quick Immune Support
9.0/10
Calmol 4
8.8/10

Best Otc Hemorrhoid Suppositories

Are hemorrhoids causing daily discomfort? Discovering the best OTC suppositories can be a game-changer, offering swift relief and soothing relief from irritation. Dive into our curated guide to find the perfect mini-miracle for your peace of mind and comfort.

Best Cheap Pick: Rugby Hemorrhoidal Suppositories

Rugby Easy Open Hemorrhoidal Suppositories Cocoa Butter 88.44% / Phenylephrine HCl 0.25% - 12 Suppositories
Highlights
Effective relief
Easy to open
Consistent quality

As our "Best Cheap Pick," it hits the sweet spot between affordability and effective relief.

The inclusion of phenylephrine HCl means you get quick, targeted symptom relief without breaking the bank.

Its easy-open packaging makes application hassle-free, which is a bonus during those uncomfortable flare-ups.

While it’s true that it can melt or crumble if not stored properly—requiring refrigeration—it’s a small trade-off for budget-conscious consumers looking for reliable relief.

If affordability without sacrificing quality is your goal, this suppository is definitely worth considering.

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Price history for Rugby Hemorrhoidal Suppositories on Amazon

Best for Postpartum Recovery: Boiron HemCalm

Boiron HemCalm Suppositories for Hemorrhoid Relief of Pain, Itching, Swelling or Discomfort - 10 Count
Highlights
Effective symptom relief
Plant-based ingredients
Cost-effective option

Boiron HemCalm Suppositories stand out as a gentle, plant-based solution that effectively reduces swelling and soothes internal hemorrhoids, especially after childbirth.

The homeopathic ingredients like witch hazel and horse chestnut work naturally to relieve burning, itching, and pain.

Plus, they're free of parabens, dyes, and preservatives, making them a safer choice for postpartum use.

While some users may experience a slight initial discomfort, the overall relief and gentle formulation make HemCalm a thoughtful option for new moms looking for comfort and reassurance during recovery.

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Price history for Boiron HemCalm on Amazon

Best for Natural Relief: Ariella Hemorrhoid Suppository

Hemorrhoid Treatment Suppository for Itch Discomfort: Hemorrhoid Shrinking Suppository Herbal Nature Gel- Best Fast Cure Burning Relief (Aloe)
Highlights
Fast, soothing relief
Natural plant-based ingredients
Easy application with applicator

This herbal suppository truly stands out as the "Best for Natural Relief" with its powerful blend of plant-based ingredients.

The soothing aloe, cortex, and plant extracts work swiftly to reduce swelling, calm itching, and ease discomfort — all without synthetic chemicals.

The smooth applicator makes for a clean, simple application, especially perfect for bedtime use.

Plus, its natural ingredients are gentle yet effective, making it a great choice for those seeking a holistic healing approach.

While it’s a short-term solution, its fast-acting, natural formula makes it a top pick for quick relief.

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Price history for Ariella Hemorrhoid Suppository on Amazon

Best for Quick Immune Support: Preparation H

Preparation H Hemorrhoid Suppositories For Itching And Discomfort Relief - 12 Count (Pack of 1)
Highlights
Effective pain relief
Soothes irritation quickly
Trusted brand recommendation

Preparation H Medicated Suppositories are a trusted choice for quick, effective relief from internal hemorrhoids.

The soothing formula rapidly eases pain and itch, making it a go-to for comfort during flare-ups.

What sets it apart is its reputation as the number 1 doctor recommended brand—a real confidence booster.

Though the packaging can be a bit tricky and the price slightly higher online, its proven effectiveness and quick soothing action make it a solid pick for those seeking fast relief.

Perfect for those who want dependable, swift results.

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Price history for Preparation H on Amazon

Calmol 4

Calmol 4 Hemorrhoidal Suppositories with Soothing Natural Ingredients, 24 Count
Highlights
Natural ingredients
Easy to use
Doctor recommended

Calmol 4 suppositories are a gentle yet effective choice for those experiencing mild to moderate hemorrhoid discomfort.

Made with natural ingredients like Cocoa Butter and Zinc Oxide, they soothe inflammation and promote healing without the harsh side effects of steroids or anesthetics.

The unique bulb shape ensures easy insertion and comfortable retention.

While they may not be powerful enough for severe cases, their doctor-recommended formula offers peace of mind and practical relief for everyday discomfort.

Overall, a solid option for natural, simple hemorrhoid care.

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Price history for Calmol 4 on Amazon

Doctor Butler's

Doctor Butler’s Hemorrhoid & Fissure Ointment – Hemorrhoid Treatment and Hemorrhoid Cream with Lidocaine and Phenylephrine HCI for Fast Acting Relief of Pain, Swelling, Discomfort, and Itching (1 oz.)
Highlights
Fast-acting numbing relief
Multi-symptom relief
Natural healing ingredients

Doctor Butler’s hemorrhoid ointment offers rapid relief thanks to its powerful lidocaine numbing cream, ideal for alleviating discomfort quickly.

Developed by a Proctologist, its blend of herbs, essential oils, and minerals promotes healing while soothing irritated skin.

Plus, its multi-symptom approach tackles pain, itching, swelling, and fissures all at once—making it a versatile choice for those needing lasting relief.

Although it does require frequent reapplications and comes at a higher price point, the cruelty-free standards and Made in the USA assurance give us added confidence.

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Price history for Doctor Butler's on Amazon

Revivol-XR Otc Hemorrhoid Suppositories

Advanced Hemorrhoid Treatment. 5% Lidocaine + Phenylephrine (Swell) + Glycerin (Protectant) + Aloe + Witch Hazel + Botanicals. Most Complete OTC Ointment & Fissure Cream, USA Made
Highlights
Fast-Acting Relief
Contains Herbal Extracts
Easy to Use

The fast-acting formula starts soothing discomfort quickly with 5% Lidocaine, giving instant relief from pain and itching.

Enriched with herbal extracts like horse chestnut and calendula, it not only calms irritated skin but also promotes healing.

The inclusion of phenylephrine helps shrink swelling, making it more comfortable to sit and move.

Plus, its creamy, non-greasy texture absorbs swiftly for easy application—perfect whether you're dealing with internal or external hemorrhoids.

Made in the USA with quality ingredients, it's a reliable, gentle option that restores comfort efficiently.

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Price history for Revivol-XR on Amazon

Ebanel Hemorrhoid Ointment

Ebanel 4% Lidocaine Hemorrhoid Treatment Ointment with Phenylephrine, Hydrocortisone, Vitamins B6, D3, E, Zinc Oxide, External and Internal Hemorrhoids Treatment Burn Itch Pain Relief Anal Cream
Highlights
Fast, long-lasting relief
Clinically proven ingredients
Comfortable, skin-soothing barrier

It combines clinically proven ingredients like Lidocaine and Phenylephrine to deliver quick, powerful relief from pain, itching, and burning.

The added boost of Hydrocortisone, Vitamin B6, Ginseng, and Chamomile helps shrink swelling and soothe irritation, offering both immediate comfort and reduced inflammation.

Plus, it forms a protective barrier with Vitamin D3 and Zinc Oxide, promoting healing.

The rich, moisturizing formula stays put, providing long-lasting relief without feeling greasy.

Made in the USA, it's a trusted, hypoallergenic choice—though a few users may experience a mild burning sensation initially.

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Price history for Ebanel Hemorrhoid Ointment on Amazon

Preparation H

Preparation H Hemorrhoid Suppositories for Itching and Discomfort Relief - 24 Count
Highlights
Effective night relief
Fast soothing action
Doctor recommended brand

Preparation H Hemorrhoid Suppositories are a trusted choice, being the number 1 doctor-recommended brand for hemorrhoid relief.

They deliver rapid soothing to ease pain and itching caused by internal hemorrhoids, making them perfect for those urgent moments.

The package of 24 offers convenient relief when you need it most, and the formulation is crafted to help reduce swelling and irritation effectively.

While the suppositories can sometimes melt during delivery and the online availability is limited, their fast acting relief and proven effectiveness make them a solid pick for quick, dependable comfort.

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Price history for Preparation H on Amazon

Preparation H Otc Hemorrhoid Suppositories

Preparation H Hemorrhoid Ointment, Itching, Burning and Discomfort Relief - 1 Oz Tube
Highlights
Quick symptom relief
Experts recommend it
Reduces swelling effectively

Preparation H Hemorrhoid Ointment offers rapid relief from burning, itching, and pain, making it a go-to for quick comfort.

Its ability to shrink swollen tissue tackles hemorrhoid symptoms at their source, while being doctor recommended adds an extra layer of trust.

We appreciate its ease of use—just perfect for external application.

Keep in mind, though, that repeated use is necessary for sustained relief, and some might experience irritation.

Overall, it’s a reliable, effective option for those seeking fast relief from hemorrhoids.

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Price history for Preparation H on Amazon

Biom Probiotics

RectiBiom Probiotic Hemorrhoid Relief Suppositories with Skin Soothing Natural Ingredients, Fast Relief. Hyaluronic Acid and Turmeric Extract, Vegan, Gluten-Free Formulation
Highlights
Natural, safe ingredients
Fast, effective relief
Vegan and hypoallergenic

RectiBiom Suppositories leverage a probiotic powerhouse combined with hyaluronic acid to deliver quick, soothing relief.

The natural ingredients—including coconut fatty acids, turmeric extract, and probiotics—work together to lubricate, heal, and reduce inflammation, making them a game-changer for internal hemorrhoids.

Plus, they're vegan, paraben-free, and made in the USA, tickling our eco-conscious side.

While the soft consistency makes application a bit tricky and the price is higher, we appreciate their quality, safety, and the rapid relief they offer.

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Price history for Biom Probiotics on Amazon

Tucks

TUCKS Medicated Cooling Pads, 100 Count – Pads with Witch Hazel, Cleanses Sensitive Areas, Protects from Irritation, Hemorrhoid Treatment, Medicated Pads Used By Hospitals
Highlights
Immediate cooling relief
Gentle cleansing and soothing
Effective for post-partum

TUCKS Medicated Pads deliver immediate cooling relief that’s perfect for soothing discomfort after a long day or childbirth.

The gentle witch hazel formula cleanses and calms irritated skin, making it a trusted choice for sensitive areas.

Its versatile design allows for use as a moist compress or a quick wipe, providing multi-layered relief.

Although you'll need to reapply every few hours, this frequent refresh keeps irritation at bay.

Overall, TUCKS offers a reliable, soothing solution for external hemorrhoid relief — a handy, go-to product when comfort is the priority.

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Price history for Tucks on Amazon

Dulcolax Otc Hemorrhoid Suppositories

Dulcolax Stimulant Laxative Medicated Suppositories, Predictable & Effective Constipation Relief, Bisacodyl 10 mg, 28 Count, Stimulant Laxatives
Highlights
Fast relief in 15-60 min
Locally targets source
Doctor recommended brand

Dulcolax suppositories deliver fast relief, often working within 15 to 60 minutes—perfect when you're on the go.

They target the source directly by delivering active bisacodyl into the rectum, stimulating natural bowel movements.

The comfort-shaped design makes insertion easier and more comfortable.

Plus, being a doctor-recommended brand adds to its credibility.

While the packaging can be a bit challenging to open, the swift, effective results make it worthwhile.

For anyone seeking quick, localized relief in a compact package, Dulcolax is a reliable choice.

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Price history for Dulcolax on Amazon

Healing Bottoms

Anal Fissure Suppository | Expert Formulation for Rectal Bleeding Due to Anus Fissure, Hemorrhoids, Diarrhea, & Constipation | Made with Natural Curcumin & Turmeric Extract | 16ct
Highlights
Fast, effective relief
All-natural ingredients
Supports healing fissures

Healing Bottoms' suppositories act quickly to soothe rectal discomfort and support healing thanks to their all-natural blend of diarylheptanoids, turmeric, and curcumin.

Their holistic approach combines multiple benefits, easing pain, reducing inflammation, and promoting tissue repair—all without harsh chemicals.

Plus, they're designed for a smooth, cooling insertion that makes relief easy.

While they require refrigeration and may stain underwear, their effective and gentle formula makes them a great choice for those seeking natural, fast-acting relief with a conscience.

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Price history for Healing Bottoms on Amazon

Naticura Hem-Control

Hem-Control - Fast Effective Hemorrhoid Treatment Supplement - Powerful Formula to Promote Symptom Relief, Shrinking of Hemorrhoids, Ease Discomfort - 90 Vegan Capsules - Made in USA
Highlights
Fast and long-lasting relief
Potent herbal ingredients
Safe and all-natural

Hem-Control offers fast and long-lasting relief by targeting hemorrhoids from the inside.

Its potent herbal blend, including Diosmin, Hesperidin, and Horse Chestnut extract, works to calm irritation and itching, promoting healthier tissue.

Although it may have limited effects on external hemorrhoids and won't stop bleeding or numb pain, it's safe, natural, and vegan-friendly, making it a reliable choice for many.

Plus, it helps normalize bowel movements, reducing the straining that often worsens hemorrhoid symptoms.

Overall, Hem-Control is a solid, research-backed option that delivers dependable relief without harsh chemicals.

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Price history for Naticura Hem-Control on Amazon

HemRid Otc Hemorrhoid Suppositories

Maximum Strength Lidocaine Cream for Pain Management. Fast-Acting Hemorrhoid Solution with 5% Lidocaine. Instant Anal Itch and Numbing Effect
Highlights
Fast-acting pain relief
Maximum strength lidocaine
Easy to apply

LMB Lidocaine 5% cream delivers maximum strength pain relief in a quick, no-fuss application.

Its fast-acting formula desensitizes nerves instantly, offering rapid relief from burning, itching, and discomfort.

The cream’s smooth texture makes it easy to apply, giving your behind much-needed rest during flare-ups.

Although it’s a bit on the pricier side and requires a thorough massage for full absorption, its efficacy and ease of use make it a top choice for anyone serious about easing hemorrhoid pain.

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Price history for HemRid on Amazon

Preparation H

Preparation H Hemorrhoid Flushable Wipes with Witch Hazel for Skin Irritation Relief - 48 Count (Pack of 4)
Highlights
Gentle cleansing with witch hazel
Biodegradable and septic safe
Provides quick hemorrhoid relief

These Preparation H Hemorrhoid Wipes with Witch Hazel offer gentle, everyday cleansing with soothing aloe and witch hazel, making them perfect for quick relief and maintenance.

The medicated wipes help reduce irritation while keeping the area fresh and clean.

Plus, they are biodegradable and septic safe, so they’re eco-friendly too.

While the packaging might be a bit flimsy and small for frequent use, their rapid soothing benefits and ease of use make them a top choice for discreet hemorrhoid care.

Be sure to also check out the best ice pack for hip bursitis for more options! Also, here is the price history so you know exactly when to buy!

Price history for Preparation H on Amazon

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