Best Probiotic for Colic
Discover the soothing power of probiotics and unlock gentle relief for your little one’s colic discomfort. In our quest for the best probiotic for colic, we’ve sifted through the most effective, safe, and gentle options that bring comfort with every dose. Get ready to navigate the world of probiotics and find the perfect match to help your baby settle into peaceful, happy moments.
Top Low-Cost Selection: BioGaia
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| Relieves colic and gas |
| Safe for newborns |
| Natural breast milk ingredients |
BioGaia Baby is the top low-cost selection for colic relief, offering a highly researched probiotic backed by extensive studies.
It naturally works within the digestive system to soothe fussiness, gas, spit-ups, and even occasional discomfort.
Plus, it’s safe for newborns from day one—free from allergens, dairy, soy, gluten, and artificial ingredients.
While it may take a few days to see results and some bottles might be underfilled, the scientifically validated ingredients and trusted safety profile make it a smart, affordable choice for parents seeking gentle, effective relief.
Be sure to also check out the best probiotic for lactose intolerance for more options! Also, here is the price history so you know exactly when to buy!
Best for Colic Relief: Mommy's Bliss
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| Supports digestive health |
| pediatrician recommended |
| Easy squeeze bottle |
Mommy's Bliss Baby Probiotic Drops Everyday are clinically shown to reduce crying and fussiness, making them our top pick for best probiotic for colic.
Backed by trusted pediatricians and crafted with the most researched probiotic strains, these drops support a healthy gut and soothe stomach discomfort.
The easy-squeeze bottle makes administration simple for busy parents, though you'll want to be mindful of the small size and heat sensitivity.
Overall, this probiotic offers gentle, effective relief without fuss, helping little ones feel happier and more comfortable.
Be sure to also check out the best probiotics for liver for more options! Also, here is the price history so you know exactly when to buy!
Best for Digestive Support: Lovebug Probiotics
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| Includes Vitamin D |
| Effective digestion support |
| Organic and allergen-free |
Lovebug Probiotics stands out as the best for digestive support for little ones aged 0-12 months.
Crafted with multi-strain organic probiotics, it offers comprehensive immune and digestive benefits.
The added Vitamin D helps build strong bones, while its allergen-free, USDA Organic certification ensures safety and purity—perfect for sensitive baby tummies.
Although the dropper can be a bit tricky to measure accurately, the effectiveness and quality assurance more than make up for it.
Overall, it's a trusted choice for parents seeking a gentle, natural way to ease colic and promote healthy digestion in their infants.
Be sure to also check out the best probiotics for alcohol drinkers for more options! Also, here is the price history so you know exactly when to buy!
Culturelle Baby
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| Clinically studied probiotics |
| Gentle for infants |
| Easy to administer |
Culturelle Baby Digestive Calm + Comfort Drops stands out as the #1 pediatrician-recommended probiotic brand, making it a trusted choice for countless parents.
It contains two of the most clinically studied probiotics proven to help with common tummy troubles and fussiness, naturally easing infant colic.
The gentle, safe ingredients ensure peace of mind, and it's incredibly easy to administer—just a quick shake and a five-drop dose.
While the dropper can be a bit tricky to use, the peace of mind it provides makes it worth it.
Overall, a solid, safe option for building a healthy foundation in your little one's first year.
Be sure to also check out the best probiotic for histamine intolerance for more options! Also, here is the price history so you know exactly when to buy!
BioGaia Protectis Baby
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| Relieves colic and gas |
| Safe for newborns |
| Natural ingredients |
BioGaia Baby is a trusted choice backed by over 20 years of research, making it the most studied probiotic for colic worldwide.
It works naturally within baby's delicate digestive system to soothe fussiness, gas, spit-ups, and even occasional constipation.
Plus, it's completely safe for newborns from day one, whether breast-fed or bottle-fed.
The fact that it contains probiotics naturally found in breast milk is a major plus, promoting a happy tummy without artificial additives.
While it may be a bit pricey and require patience, many parents find it worth the wait for those calmer, more comfortable days.
Be sure to also check out the best probiotic for mouth ulcers for more options! Also, here is the price history so you know exactly when to buy!
Culturelle Probiotics for Babies Probiotic for Colic
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| Helps soothe fussiness |
| Supports digestive health |
| Easy to administer |
Culturelle Baby Colic plus Soothing Probiotic Drops offers a gentle, natural way to help soothe your little one's fussiness caused by digestive discomfort.
The inclusion of 100% of the daily vitamin D boost makes it a smart choice for supporting strong bones.
It's easy to use — just five drops a day directly into the mouth or bottle, making it super convenient for busy parents.
Plus, it features safe, natural ingredients and is free from common allergens like dairy, gluten, and soy.
While the bottle size is small and a bit pricier, its effectiveness in supporting your baby's digestive health makes it a solid pick.
Be sure to also check out the best probiotic for low fodmap for more options! Also, here is the price history so you know exactly when to buy!
MaryRuth Organics Baby Probiotic Drops
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| Clinically Studied Strains |
| Supports Gut Health |
| Easy to Administer |
MaryRuth’s Organic Infant Probiotic Drops are clinically studied with proven strains like Pediococcus pentosaceus and Bifidobacterium longum, targeting those pesky colic symptoms.
The easy-to-drop liquid formula makes administration a breeze—just up to 5 drops daily—and it’s suitable for babies 0-12 months.
Plus, it’s organic, vegan, and free from common allergens, making it a safe choice for sensitive tummies.
While some parents have mentioned minor issues like bottle clogging or messiness, overall, this probiotic supports gut health and may help reduce crying, making it a solid pick in our review.
Be sure to also check out the best probiotic for hemorrhoids for more options! Also, here is the price history so you know exactly when to buy!
Mylicon
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| Clinically reduces crying |
| Supports immune health |
| Easy to use |
Infants' Mylicon Daily Probiotic Drops are a game-changer for easing colic discomfort.
They’re clinically proven to reduce crying and fussiness when used regularly, helping your little one feel calmer faster.
Plus, they support a healthy immune system by replenishing beneficial bacteria depleted during antibiotics or illness.
The drops are versatile—just add to a bottle, feed directly, or apply on the breast—making it super convenient for busy parents.
Safe and free from common allergens like gluten, dairy, and nuts, these drops are a trusted choice by many.
We love how simple and effective they are for calming those restless little tummies.
Be sure to also check out the best probiotics for gallbladder for more options! Also, here is the price history so you know exactly when to buy!
MaryRuth Organics Probiotic for Colic
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| Supports infant gut health |
| Easy to administer drops |
| Organic and allergen-free |
MaryRuth's Infant Probiotic Drops are a top contender for soothing colic thanks to their organic, allergen-free formulation.
The drops are super easy to give — just a single drop directly in your baby's mouth or added to a drink.
The blend features five probiotic strains, including Bacillus coagulans, designed to support healthy gut development.
While the CFU count is modest, the clean, vegan, and hypoallergenic profile makes it a great choice for sensitive tummies.
Plus, the certified organic label provides peace of mind.
Overall, a gentle, high-quality option for your little one.
Be sure to also check out the best probiotics for fibromyalgia for more options! Also, here is the price history so you know exactly when to buy!
Pink Stork
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| Supports healthy digestion |
| Easy to administer |
| No artificial ingredients |
Pink Stork’s Baby Probiotic Drops deliver 1 billion CFU of Lactobacillus rhamnosus—the most studied probiotic strain—recommended by pediatricians.
The no-drip syringe makes administering a breeze, fitting seamlessly into busy parents' routines.
Plus, it’s vegan, gluten-free, and free of artificial ingredients, aligning with clean-eating values.
While some have noted packaging issues, the probiotic’s support for digestive comfort and immune health* makes it a solid choice for easing fussiness and gas.
Ultimately, it’s a reliable, kid-friendly probiotic that parents can trust for daily digestive support.
Be sure to also check out the best probiotics for osteoporosis for more options! Also, here is the price history so you know exactly when to buy!
Wellements Organic Baby Probiotic
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| Supports digestive health |
| Clean, organic ingredients |
| reduces fussiness |
The Organic Probiotic Drops from Wellements are a natural, gentle way to support your baby’s gut health.
Made with high-quality probiotics like LactoSpore Bacillus coagulans and organic MCT oil, these drops are certified organic, vegan, and free from artificial nasties.
They seamlessly blend into breast milk or formula, making administration super easy—simply drop, mix, and go!
While they do require refrigeration and come with a slightly higher price point, their effectiveness in reducing fussiness and supporting overall digestion makes them a star choice for concerned parents seeking a safe and reliable probiotic for colic relief.
Be sure to also check out the best probiotics for gout for more options! Also, here is the price history so you know exactly when to buy!
Mommy's Bliss Probiotic for Colic
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| Easy to administer |
| Tasteless drops |
| Supports digestion |
Mommy's Bliss Baby Probiotic Drops + Vitamin D are gentle, safe, and easy to use — perfect for even the tiniest tummies.
The tasteless drops make administration a breeze, and the added Vitamin D helps support overall immune health.
While some parents might wish for more extensive review data or quicker results, its reputation for supporting digestion and easing colic is well-earned.
Just remember to be available during delivery to avoid melting issues!
Overall, it's a trusted choice that offers healthy, happy babies and peace of mind for parents.
Be sure to also check out the best probiotic for sugar cravings for more options! Also, here is the price history so you know exactly when to buy!






